2018-06-20, NEWS

AI for prostate cancer analysis

A new study led by Joakim Lundeberg (KTH/SciLifeLab) demonstrates that tumor heterogeneity in prostate cancers can be characterized using an AI approach. The results are published in Nature Communications.   Each cancer is unique and also alters its features as it progresses. The underlying genetic changes of this heterogeneity can be of clinical relevance to cancer […]

2018-06-12, NEWS

Cold-water sponges from different geographical areas share the same microbiota

In a novel study researchers have compared the microbiota of two species of sponges belonging to the genus Mycale from the sub-Antarctic Magellan region and the Western Antarctic Peninsula. High throughput sequencing performed by SciLifeLab National Genomics Infrastructure revealed a remarkable similarity in the microbiota of Mycale (Aegogropila) magellanica and Mycale (Oxymycale) acerata, although they live in geographically distant areas with contrasting environmental […]

2018-06-12, NEWS

Dog skeletal cancer genomics resembling human counterpart

The genes TP53 and SETD2 are often mutated in dogs suffering from skeletal cancer, according to a novel study led by Kerstin Lindblad-Toh (Uppsala University/SciLifeLab). The pattern found is similar to the ones in human skeletal cancers; clearly establishing that knowledge from canine studies can contribute to understanding of corresponding diagnoses in humans. Skeletal cancer is […]

2018-06-12, NEWS

Therapeutic gene editing may increase cancer risk

Using the recognized DNA-altering CRISPR-Cas9 technique to treat diseases may inadvertently increase the risk of cancer, according to a new study co-supervised by Bernhard Schmierer (Karolinska Institutet) who heads the High Throughput Genome Engineering facility at SciLifeLab. The results are published in Nature Medicine. CRISPR-Cas9 is a molecular machine that can be programmed to find a precise […]

2018-06-11, NEWS

SciLifeLab mobilizes expertise and technologies around seven research themes

To facilitate internationally competitive, cutting-edge collaborative research, SciLifeLab now announces its support for seven Research Community Programs – networks that will connect top researchers across Sweden with each other and with the SciLifeLab infrastructure. In February 2018, SciLifeLab launched a national call for Research Community Programs (RCPs) and seven applications from different research areas were […]

2018-06-08, NEWS

Ectomycorrhizal fungi play contrasting roles in decomposition of organic matter

A recent study enabled by the National Genomics Infrastructure shows that ectomycorrhizal fungi play contrasting roles in decomposition of organic matter. The researchers, led by Björn D. Lindahl at Swedish University of Agricultural Sciences (SLU), showed that exclusion of tree roots and associated ectomycorrhizal fungi in a boreal forest increased decomposition of surface litter by 11%. On the […]