The Silent Crisis in Oncology Real-World Evidence — and How to Fix It
March 27, 2026 @ 15:00 – 16:00 CET
Asieh Golozar, founder and CEO of Nemesis Health
The programme includes a 40-minute talk followed by a 20-minute Q&A session
Biography
Asieh Golozar is the founder and CEO of Nemesis Health, a company dedicated to progressing cancer research through large scale real-world evidence from a network of cancer centers. She is a physician-epidemiologist and biostatistician with more than 20 years of experience in real-world evidence generation, observational research and evaluation of healthcare interventions within government, academia, and industry.
Asieh holds a PhD in Epidemiology from the Johns Hopkins University and a Master of Health Sciences in Biostatistics from Johns Hopkins University School of Public Health, supported by a postdoctoral research fellowship award with the National Cancer Institute’s Division of Cancer Epidemiology and Genetics. She earned her medical degree from Tehran University of Medical Sciences.
After her education, she joined the faculty at the Johns Hopkins University Department of Epidemiology, where she focused on cancer and diabetes epidemiology, the application of epidemiologic and statistical methods for robust synthesis of evidence from epidemiologic data and applying evidence-based findings to strengthen public heath infrastructure and policies. She then transitioned into industry roles at Bayer AG, AstraZeneca, and Regeneron, where she led lifecycle management and real-world evidence generation activities in oncology, women’s health, and other therapeutic areas.
Currently, Golozar holds the position of professor of the practice at Northeastern University, where she is engaged in epidemiological methodology and statistics for real-world evidence. She holds faculty appointments at Johns Hopkins University in the Department of Epidemiology and the Division of GeneralInternal Medicine at the School of Medicine. Additionally, she is the leader of the Oncology Working Group at OHDSI, a global open source and open science collaborative.
Abstract
High-quality real-world evidence (RWE) in oncology requires detailed clinical data, standardized representations of tumor characteristics, and analytic methods that can be reproduced across institutions and health systems. Most oncology datasets remain fragmented, differ in structure, and lack the granularity needed to study treatment patterns, biomarker-driven care, disease trajectories, and outcomes at scale. The OMOP Common Data Model, together with oncology-specific conventions, provides a harmonized framework for representing diagnoses, histology, stage, biomarkers, treatments, and outcomes in a way that supports transparent and reproducible analytics.
FALCON (Federated Alliance for Large-Scale Oncology Research) is a growing international network built on this foundation. It enables federated studies using shared methods while keeping data securely within each institution. Early applications of this approach have demonstrated its ability to characterize real-world treatment patterns, evaluate guideline relevance, study disease progression, and support methodological development across diverse populations and health-care environments.
This talk will present the scientific foundations, methodological considerations, and early results demonstrating how standardized data and federated analytics can advance oncology RWE. The work highlights opportunities for deeper collaboration across pathology, oncology, genomics, and data science to build scalable, trustworthy real-world evidence for cancer research.
About Clinical Talks
Clinical Talks returns with a new season!
After seven successful seasons and over seventy dedicated speakers, we are excited to continue showcasing the contributions of our diverse clinical, academic, and industry life science community. This season will feature ten insightful talks following our well-established format.
The overarching theme is “How to Achieve Feasible Implementation.” Sessions are held monthly ,usually on Fridays via Zoom, with occasional exceptions. Each talk will be followed by an engaging Q&A session, moderated by standing host Rikard Fred and a guest moderator with subject matter expertise to enrich the discussion.
In today’s rapidly evolving post-pandemic landscape, exploring how academic, clinical, and industry research, combined with technological advancements, can drive practical and sustainable solutions is crucial. Join us for an opportunity to gain fresh insights, expand your knowledge, and connect with experts shaping the future of life sciences!
Clinical Talks are organised by SciLifeLab.
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