Decoding Enhancer-Mediated Gene Regulation with CAGE-seq and Deep Learning
Michiel de Hoon, RIKEN center, Japan Abstract Precise regulation of gene expression is fundamental to cellular identity and behavior, and gene dysregulation is a common feature across a wide variety of diseases. At the molecular level, this regulation is orchestrated by transcription factors acting on non-coding regulatory elements at promoters and distal enhancers. Genome-wide association studies have […]