New units presentation: CBCS Uppsala

CBCS Uppsala provides morphological profiling through Cell Painting, a high-content imaging approach for studying cellular responses at scale. The unit is part of the Chemical Biology Consortium Sweden (CBCS) and is now supported within SciLifeLab’s infrastructure.

Based at Uppsala University, the facility combines automated imaging, robotics, and data analysis to enable large-scale phenotypic screening. It supports a growing field where biological insight is derived from complex, image-based data.

What CBCS Uppsala offers

The unit runs Cell Painting assays that capture thousands of morphological features from cells in parallel. This enables detailed analysis of how compounds, genetic perturbations, or disease states affect cellular systems.

Workflows are highly automated and designed for large-scale studies, including screening in multi-well formats. The facility also provides tailored data analysis, supported by dedicated computational infrastructure for handling large imaging datasets.

Researchers from academia and international collaborations use the platform for applications such as mechanism-of-action studies and compound characterization. Each project is developed in close dialogue with users to ensure that experimental design matches the research question.

As part of SciLifeLab, CBCS Uppsala continues to develop new capabilities, including more advanced cell models and data analysis approaches, while supporting increasing demand for phenotypic screening.

Visit the CBCS Uppsala website (scroll down to nodes and click on Uppsala)