Today

    • Role of physiologically-based pharmacokinetics in regulatory submissions

    AbstractPhysiologically based pharmacokinetic (PBPK) is an approach that help predict the absorption, distribution, metabolism and excretion (ADME) properties of candidate drugs in animal/human and evaluate the effects of intrinsic (e.g. organ dysfunction, age, genetics) and extrinsic (e.g. diet, smoking habit, drug-drug interactions) factors, alone or in combinations, on drug exposure, during drug discovery and development […]

    Drug Discovery and Development Platform (DDD)
    Virtual Event

    • Drug Discovery Seminars: An adaptable Drug Affinity Conjugate (ADAC) targeting CD40

    Proof of Concept and Pharmaceutical profiling Sara Mangsbo, Uppsala University Abstract: Much attention has focused on developing CD40 directed agonistic monoclonal antibody therapy. Monoclonal antibodies targeting CD40 have been profiled for their epitope specificity and isotype in relation to their agonistic potential. Still, clinical impact relies on a well-balanced clinical efficacy versus target-mediated toxicity. As CD40-mediated […]

    Drug Discovery and Development Platform (DDD)
    Virtual Event

    CryoEM in Drug Discovery

    Session 1 All time slots below are in UTC+2 / CEST Time zone . June 8th – Afternoon 14:00Welcome wordsAnnika Jenmalm-Jensen, Infrastructure Director, SciLifeLab14:05Introduction to the cryo-EM Unit at SciLifelabMarta Carroni, SciLifeLab/Stockholm University, Sweden14:15From Concept to Reality: CryoEM as an Integral Part of Drug Discovery and Development Corey Strickland; Merck, Kenilworth, United States14:55CryoEM at AstraZenecaChris Phillips; Astra […]

    Drug Discovery and Development Platform (DDD)
    Virtual Event

    • [Drug Discovery Seminars] Targeting the oncogenic TGFβ signaling pathway in cancer to inhibit invasion and metastasis

    Maréne Landström October 28, 13:00-14:00 Welcome to join this Drug Discovery Seminar hosted by the Drug Discovery and Development Platform. Presenter: Professor Maréne Landström, M.D., PhD Dept. Medical Biosciences, Umeå University Maréne Landström is a professor in Pathology at Department of Medical Biosciences, Umeå University, Sweden. She has made her postdoctoral training at the Ludwig Institute of Cancer Research, […]

    Drug Discovery and Development Platform (DDD)
    Online event via Zoom
    Virtual Event

    • [Drug Discovery Seminar] How protein degradation led to faculty entrepreneurship at Yale: A personal Perspective

    SciLifeLab Drug Discovery Seminars, hosted by the DDD platform, is a series of educational lectures about recent developments, technologies, and trends in drug discovery and development that aims to enlighten, and spark a discussion, within the Swedish drug discovery community. Craig Crews John C. Malone Professor of Molecular, Cellular, and Developmental Biology and Professor of […]

    Drug Discovery and Development Platform (DDD)
    Air&Fire, SciLifeLab Stockholm Tomtebodavägen 23A, Solna, Sweden