Technology Development Projects (TDPs)
The projects in the list below have been approved by the SciLifeLab board to receive TDP funding. Part of the funding came from the national SciLifeLab infrastructure funding, while most of it was contributed by the Strategic SciLifeLab funding (SFO) received by the four host universities KTH, KI, SU and UU.
Annika Jenmalm Jensen, Infrastructure Director of SciLifeLab, explains the importance for SciLifeLab to support technology development and explore new technologies that could enable breakthrough discoveries to be made in the future
“The purpose of the TDPs is to help SciLifeLab national infrastructure units to offer improved and new services and to keep the SciLifeLab infrastructure at the cutting-edge.”
Annika Jenmalm Jensen, Infrastructure Director at SciLifeLab.
Approved Technology Development Projects 2026-2027
- Time-resolved cryo-EM – resolving molecular mechanisms at the milliseconds and microseconds scale
Marta Carroni (SU), Sebastian Westenhoff (UU), Filipe Maia (UU), Magnus Andersson UmU) - Spatial miRNomics
Rapolas Spalinskas (SU), Mats Nilsson (SU), Agustin Robles (SU) - Reshaping Bio NMR by AI: Fully automated assignment and structure in hours
Ulrika Brath (GU), Vladislav Orekhov (GU) - Spatial multiomics integration
Åsa Björklund (Chalmers), Joakim Lundeberg (KTH), Charlotte Stadler (KTH), Katarina Tiklova (SU), Anna Nilsson (UU), Anja Mezger (KTH) - From Correlation to Causation: Linking CRISPR Perturbation with Cell- and Tissue Profiling at Scale
Bernhard Schmierer (KI), Chika Yokota (SU), Kasper Karlsson (KI), Mats Nilsson (SU) - QUICK-CN: Ultra-low-input copy-number analysis at scale
Jessica Nordlund (UU), Jan Dumanski (UU), Joakim Lundeberg (KTH), Abrahan Hernandez-Hernandez (KI) - High-Resolution Multiomics: Advanced integrated Spatial Multiomics for next-generation diagnostics
Carolina Oses Sepulveda (KTH), Katarina Tiklova (SU), Charlotte Stadler (KTH), Anders Ullén (KI), Elisabet Stener-Victorin (KI) - Q-Loop – Quality-Controlled Workflow Manager for Microscopy
Mathieu Coincon (SU), Rafael Camacho (GU), Gerhard Hofer (SU), Wei Ouyang (KTH) - Cell-specific Proteome 3D Structure Atlas by Structural Elucidation of Proteins in Cellular Environment (SEPCE)
Massimiliano Gaetani (KI), Roman Zubarev (KI) - Spatial Multi-Omics on a Single Tissue Section
Katarina Tiklova (SU), Anna Nilsson (UU), Åsa Björklund (Chalmers) - AICE – AI-guided Intracellular Cyclic-peptide Engine
Per Arvidsson (KI), Mikael Altun (KI), Patrick Bryant (SU), Ilaria Testa (KTH) - Multiplex Spatial Interactomics Integrating in-situ Proximity Ligation Assay and Cell Painting for AI-Powered Drug Discovery and Precision Medicine
Malin Jarvius (UU), Ulf Landegren (UU), Ola Spjuth (UU), Xuan Wang (UU) - Enabling the next big transformation in Genomics: Combining Pangenomes and the Ancestral Combination Graph
Per Unneberg (UU), José Cerca (Swedish Museum of Natural History), Ole Tørresen (University of Oslo), Lars Feuk (UU) - BioVAT – Biodiversity Variant Analysis Toolkit
Henrik Lantz (UU), Niclas Backström (UU), Mafalda Ferreira (SU), José Cerca (Swedish Museum of Natural History), Jacob Höglund (UU) - Next-Generation Spatial Omics: Enabling Host–Microbe-Immune Insights via Smt and Spatial VDJ
Anja Mezger (KTH), Stefania Giacomello (KTH), Camilla Engblom (KI), Kim Thrane (KTH) - 3D spatial profiling of transcripts and proteins in tissue
Hans Blom, Katarina Tiklova (SU), Charlotte Stadler (KTH), Steven Edwards (KTH) - Development of a High-Accuracy, High-Throughput Droplet-PTA Platform for scWGS
Julia Bräunig (LU), Johan Henriksson (UmU), Laura Carroll (UmU), Simone Weström (UU), Åsa Björklund (Chalmers) - Capture-based long-read metagenomics for detection of pathogens and antimicrobial resistance
Bianca Stenmark (ORU), Rene Kaden (UU), Daniel Golparian (ORU) - AbPEA-NGS: Monitoring Antibody Reactivity Using High-Throughput Proximity Extension Assays
Mikael Åberg (UU), Ulf Landegren (UU), Nils Landegren (UU), Anna Szekely (SLU) - HOT-Lab: Anticipatory and Reactive Structural Biology Technologies for Pandemic Preparedness
Cecilia Persson (GU), Gemma C. Atkinson (LU), Dag Ahren (LU)
Approved Technology Development Projects 2021–2023
Click on title to view a poster describing the project.
Approved Technology Development Projects 2019–2020
- High-throughput screening in live zebrafish
- Bifunctional Protein Degrader (BIPOD) – Towards tissue selective PROTAC’s
- Eukaryotic protein production for biomedical research
- Mass Spectrometry Imaging in Neuroscience (Neuro-MSI)
- MF-SIM: Live Cell Super-Resolution 4D-Microscopy
- High -dimensional secretomic analysis of single cells for systems-level immunomonitoring
- Production of proteins and glycoproteins in mammalian cells
- Ultra-sensitive monitoring of tumor DNA in plasma from cancer patients
- Novel method for identifying the effect of DNA sequence variants on common diseases
- Multiplexed imaging tools for high-dimensional protein maps of human cells and tissues
- Spatial Genomics
- Deep and quantitative phosphoproteomic profiling of biological samples
- RIF-Seq: RNA isolation free RNA sequencing
- CRISPR Screening 2.0
- Improved drug discovery using single-cell resolution target-engagement profiling
- Artificial Intelligence and Image Analysis for Whole Slide Imaging (AIIA-WSI)