EMBL-SciLifeLab Data Science workshop

May 15, 2023 May 16, 2023
Event Tags:
DDLS

Venue

Eva von Bahr
Ångström Laboratory, Uppsala University
Uppsala, Sweden
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EMBL-SciLifeLab Data Science workshop

We would like to cordially invite members of the SciLifeLab and EMBL Communities to this workshop! This event will bring together researchers, scientific and technical staff at the EMBL and SciLifeLab, to make new acquaintances and collaborations and to learn and be inspired by each other.

The workshop program starts at 09:00 on May 15 and ends after lunch on May 16.

The workshop will be a hybrid event enabling participation to the wider community at all EMBL and SciLifeLab sites.

Looking forward to meeting you in Uppsala in May!

Sessions

  • Internal and external training and support
  • Provision of public data services – computational tools
  • Artificial intelligence
  • Integrated data management and Scientific workflow sharing
  • Technical infrastructure – computational solutions
  • Biological theme – Imaging
  • Biological theme – Human data

Participation by invitation only. Target audience: SciLifeLab and EMBL staff.

Scientific committee

  • Johan Rung, SciLifeLab
  • Carolina Wählby, SciLifeLab
  • Jan Korbel, EMBL
  • Rupert Lueck, EMBL
  • Rolf Apweiler, EMBL

Program

Monday May 15

Time slotMonday, May 15
09:00Welcome and introduction
Olli Kallioniemi, SciLifeLab and DDLS Director, and Jan Korbel, Head of Data Science, EMBL
09:15Session 1: Internal and external training and support
Themes: what is training at EMBL, Data Science training work stream -SciLifeLab training hub -Areas for synergies
Moderator: Cath Brooksbank, Head of Training, EMBL-EBI
EMBL Data Science Training: the story so far
Lisanna Paladin, Bioinformatics Community Project Manager, EMBL
SciLifeLab Training Hub: the story starts now – what are the goals?
Nina Norgren, Training manager, SciLifeLab
Panel discussion and questions on stimulating exchange and collaboration
10:20Coffee break
Mounting of posters
10:50Session 2: Provision of public data services – computational tools
Moderator: Johanna McEntyre, Associate Director for Service, EMBL-EBI
Successfully managing a portfolio of data services
Johanna McEntyre, Associate Director for Service, EMBL-EBI
Introductions to:
Metabolic atlas
Mihail Anton, NBIS expert, SciLifeLab

Protein Database
Sameer Velankar (PDB Europe), Team Leader, EMBL-EBI
Panel discussion: the future challenges and opportunities for public data services
Mihail Anton (Metabolic Atlas)
Matthew Hartley (BioImage Archive)
Cecilia Lindskog (Human Protein Atlas)
Fergal Martin (Ensembl)
Sameer Velankar (PDB Europe)
11:55Lunch
Poster session
13:15Session 3: Artificial Intelligence
Moderator: Carolina Wählby, Scientific Director of BioImage Informatics and Group Leader, SciLifeLab
AI in Image Analysis
Anna Kreshuk, Group Leader, EMBL
AI in Cancer genomics, prediction of treatment
Isidro Cortes-Ciriano, Group Leader, EMBL-EBI
AI in spatial omics
Carolina Wählby, Scientific Director of BioImage Informatics and Group Leader, SciLifeLab
Serving AI models
Ola Spjuth, Group Leader and AI coordinator, SciLifeLab
Discussion on how to foster AI further
14:20Coffee break
Poster session
14:50Session 4: Integrated data management and scientific workflow sharing
Moderator: Henning Hermjakob, Head of Molecular Systems, EMBL-EBI
Expression Atlas
Irene Papatheodorou, Team Leader – Gene Expression, EMBL-EBI
Complex Workflows
Mats Nilsson, Platform Director Spatial Biology and Group Leader, SciLifeLab
Discussion
15:55Short break
16:00Session 5: Technical infrastructure – computational solutions
Moderator: Johan Rung, Head of Data Centre, SciLifeLab
Cloud – Beyond the hype
Andy Cafferkey, Head of Technical Services, EMBL-EBI
The IT role in empowering advanced research data management
Rupert Lück, Head of IT Services, EMBL
The great datawanderung – how sensitive data is reshaping research infrastructures. Data transfer, Compute moving to data
Johan Viklund, NBIS Chief Technical Officer, SciLifeLab
Needs and requirements to provide next generation of compute services (notebooks, containerization, GPUs, etc) – energy, carbon issues
Ola Spjuth, Group Leader and AI coordinator, SciLifeLab
17:05Wrap-up
17:10Poster session with refreshments
18:30Conference Dinner

Tuesday May 16

Time slotTuesday, May 16
09:00Session 6: Biological theme – imaging
Moderator: Anna Klemm, Head of the BioImage Informatics Facility, SciLifeLab
Image Data and Image analysis
Hjalmar Brismar, Platform Scientific Director Advanced Light Microscopy unit and Group Leader, SciLifeLab
Christian Tischer, Centre for Bioimage Analysis, Scientist/IT Engineer, EMBL
Panel discussion: Workflows from image data generation to data analysis and finally image data publication. How are projects and data managed?
Hjalmar Brismar, SciLifeLab
Matthew Hartley, BioImage Archive Team Leader, EMBL-EBI
Anna Klemm, SciLifeLab
Erik Lindahl, Group Leader, SciLifeLab
Christian Tischer, EMBL
10:05Coffee break
Poster session
10:35Session 7: Biological theme – human data
Moderator: Helen Parkinson, Team Leader SPOT, EMBL-EBI
Integrated FEGA/FDA-components/Federated Analysis
Oliver Stegle, Associate Group Leader, EMBL
Developments from Human Data Services
Bengt Persson, Platform Director NBIS, SciLifeLab
Discussion
11:40Workshop wrap-up
Carolina Wählby, Scientific Director of BioImage Informatics, SciLifeLab and Rolf Apweiler, Joint Director of EMBL-EBI
12:00Lunch
Afternoon:Self-organized break-out tech workshops, Site visits, etc

Sessions

EMBL and SciLifeLab recently launched data science training initiatives. In this session we will share our approaches to developing data science training  – our plans, our successes and our greatest challenges. An open discussion will explore areas for future collaboration and how we might work together to recognise those who dedicate their time, usually on a volunteer basis, to advanced scientific training.

Explore how to manage a portfolio of public computational tools and data services, with real-world examples from both emerging and established resources, and a panel discussion on the future challenges and opportunities for public data services

In this workshop:

  • A keynote talk introduces key points of successfully managing a portfolio of data services
  • One emerging and one established data service summarize their management approach
  • A panel discussion including other data service leads from EMBL-EBI and SciLifeLab discuss the future challenges and opportunities for public data services

In this session we will focus on how to foster AI further (within EMBL-EBI and SciLifeLab) – What are the lessons learned during the last decade of incorporating learning-based methods using neural networks in biomedical research? Where lies the power, and what are the limitations? How do we handle bottle-necks such as lack of reliably annotated training data, and how do we avoid biases introduced by factors such as sample preparation and data collection? How can we include ‘the human in the loop’, and how can we share models?

Modern, data-intensive science requires complex and ideally reproducible workflows. Based on two opening presentations, one from a complex “research” workflow background, one from a repeatable “service” background, and a subsequent panel discussion, we want to explore

  • What are the scientific demands and requirements for computational workflows?
  • How to strike the right balance between reproducibility and flexibility?
  • What is the current status and future aspirations for technical support of computational workflows?
  • What are the opportunities for coordination / integration of internal /external workflows between SciLifeLab and EMBL?

The technical infrastructures and computational solutions provided by teams across EMBL and SciLifeLab are at the heart and the critical foundation of data science activities in both institutions. In this session, we aim to initiate a cross-organizational dialogue and to set the stage for further networking among interested stakeholders to explore key IT and technical challenges and learn more about potential solutions being explored on both sides.

The session will start with four short presentations to stimulate the open discussion that will follow. Our input from the presentations will cover a wide range of technical topics and challenges:

i) key aspects of using cloud services,

ii) opportunities to improve scientific data management via dedicated IT solutions,

iii) the challenges associated with shared analysis and transfer of (sensitive) data across centres, and

iv) exploring the needs for next-gen computational, data analytics, and management services for data science in the life sciences.

In the imaging session we will discuss workflows from image data generation to data analysis and finally publication. Which paths does microscopy data take at EMBL and SciLifeLab? How can data analysis and data management be integrated early on in the project discussions? The session will also give an insight to which kind of imaging projects are handled at both EMBL and SciLifeLab, since imaging data can have a broad range of characteristics and comes with different analysis and data management needs.

The Human Data session will focus on challenges working with federated and multidimensional human data, interfacing with national data , e.g. Genomics Data Infrastructure (GDI; Persson) enabling realisation of the European 1+ Million Genome project, and the experience of working at the interface of clinical research with industrial partners, including the Mannheim alliance (Stegle) and precompetitive industrial collaborations, e.g.OpenTargets (https://www.opentargets.org/). The session will have two presentations (Stegle, Persson) followed by a panel discussion. It aims to define the skills set, mindset, technical solutions to address shared problems of human research data. 

May 15 @ 08:00 May 16 @ 17:00 CEST

Ångström Laboratory, Uppsala University
Uppsala, Sweden
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Last updated: 2023-05-14

Content Responsible: David Gotthold(david.gotthold@scilifelab.se)