HDCA Seminar Series 2022 | TissUUmaps Speakers: Carolina Wählby and Christophe Avenel We present TissUUmaps, browser-based tool for GPU-accelerated visualization and interactive exploration of tens of millions of datapoints overlaying tissue samples. Users can visualize markers and regions, explore spatial statistics and quantitative analyses of tissue morphology, and assess the quality of decoding in situ transcriptomics data. TissUUmaps […]

HDCA Seminar Series 2022 | Lung Christo Samakovlis and Alexandros Sountoulidis The lung contains numerous specialized cell-types with distinct roles in tissue function and integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a first comprehensive topographic atlas of early human lung development. We report 83 cell states, several spatially-resolved developmental trajectories and predict cell interactions within defined […]

Decoding the development of the human spinal cord by multi-omics Xiaofei Li and Erik Sundström HDCA Seminar Series 2022 | Spinal cord The human spinal cord has highly diverse cell types, which are generated during development, governed by a series of temporal and spatial events for proper spinal cord assembly and function. However, the molecular regulation of cell fate specification in the human developing spinal cord remains largely unknown. Here, by performing single-cell RNA sequencing, spatial […]