Our infrastructure

ADME of Therapeutics

UDOPP is the DDD-platform unit for absorption, distribution, metabolism, excretion (ADME) and pharmaceutical profiling.



Advanced FISH Technologies

Advanced FISH Technologies(AFT) The AFT Facility enables researchers to access our extensive expertise of DNA and RNA single-molecule fluorescence in situ hybridization (smFISH) assays and our growing repository of oligo-based […]



Affinity Proteomics

Offers custom designed solutions for high-throughput analysis of proteins in body fluids with multiplexed immunoassays.



AIDA Data Hub

AIDA Data Hub The AIDA Data Hub offers Data Sharing, Policy Support, and Services for the Swedish medical imaging diagnostics AI research community. The purpose is to gather, annotate, and share large volumes of […]



Ancient DNA

Use cleanroom labs and specialized molecular genetics techniques to extract, make libraries, sequence and analyze DNA in ancient and/or degraded biological material.



Autoimmunity and Serology Profiling

Offers analysis of the autoantibody repertoire in body fluids as well as antibody validation using custom designed protein and peptide arrays.



Biochemical and Cellular Assay

Biochemical and Cellular Assay The Biochemical and Cellular Assay unit provide the drug discovery projects in the DDD platform with enzymatic and cellular assays using microplate based technologies. We support […]



BioImage Informatics

The BioImage Informatics Unit provides the support and training you need to perform state-of-the-art analyses on your image data. Whether you are looking for training on how to use existing software solutions or help developing a custom workflow, you can get support from us.



Biophysical Screening and Characterization

The unit provides in depth information on interactions.



Cellular Immunomonitoring

Enables deep phenotypic characterization and functional profiling of millions of cells with >40 markers tagged/cell that can be readily analyzed (through CyTOF™, Fluidigm Inc.).



Chemical Biology Consortium Sweden

To explore complex biology, CBCS provides expertise and support in assay development, screening & chemistry to generate small molecules for applications in all life science research areas.



Chemical Proteomics

Chemical Proteomics The Chemical Proteomics unit (ChemProt) is a national unit expert on supporting drug discovery and development by proteome-wide deconvolution of targets and action mechanisms of small molecules. ChemProt has […]



Clinical Genomics

Develops and provides clinical genetic tests using state-of-the-art genomic methods, such as next-generation sequencing, for translational research and healthcare.



Clinical Genomics Göteborg

Clinical Genomics Göteborg Clinical Genomics Göteborg was established in January 2016 as a collaborative effort between the Sahlgrenska Academy at the University of Gothenburg and Area 4, Laboratory Medicine at […]



Clinical Genomics Linköping

Clinical Genomics Linköping Clinical Genomics Linköping was established in 2019 as a regional distributed node of the Diagnostic and Development platform of SciLifeLab and the section of molecular genetics at […]



Clinical Genomics Lund

Clinical Genomics Lund Clinical Genomics Lund was established in 2016 as a joint strategic initiative between the Medical Faculty at Lund University and the Division of Laboratory Medicine, Medical Services, […]



Clinical Genomics Stockholm

Clinical Genomics Stockholm The Clinical Genomics Stockholm unit provides a dedicated research infrastructure for projects utilising massively parallel / next generation sequencing technologies. All projects are carried out in close […]



Clinical Genomics Umeå

Clinical Genomics Umeå Clinical Genomics Umeå is a joint venture between Umeå University and the clinical laboratories at Umeå University Hospital. It operates in a tight collaboration with Genomic Medicine […]



Clinical Genomics Uppsala

Clinical Genomics Uppsala Clinical Genomics Uppsala is jointly set up by Uppsala University, Uppsala University Hospital and SciLifeLab with the aim to catalyze the transition of novel research findings into […]



Clinical Genomics Örebro

Clinical Genomics Örebro Clinical Genomics Örebro was established in 2019 as a collaborative effort between the Department of Laboratory Medicine and the Clinical Research Laboratory (KFL) at Örebro University Hospital […]



Co-Detection by Indexing (CODEX)

CODEX – high parametric imaging of cells in a tissue context Introduction/background To reveal and understand the collective behaviors of cells in the tissue context, imaging technologies are ideal since […]



CRISPR Functional Genomics

Pooled high-throughput CRISPR-Cas9 perturbation for genetic loss- and gain-of-function screens.



Cryo-EM

The Cryo-EM Swedish Infrastructure Unit offers access to state-of-the-art equipment and expertise in single particle cryo-EM and cryo-tomography (cryo-ET).



Drug Discovery and Development Platform (DDD)

Generates small-molecule and antibody leads for further progression into therapeutic applications and support with target product profiling and safety assessment of the future drug.



Eukaryotic Single Cell Genomics

Provides service for high-throughput single cell genomics analysis



Exposomics

National Facility for Exposomics The National Facility for Exposomics at SciLifeLab is coordinated by Stockholm University and the Department of Environmental Science (ACES). With expertise in small molecule mass spectrometry […]



Genome Engineering Zebrafish

Offers zebrafish target validation/disease models by CRISPR/Cas9 induced loss of function mutagenesis in relevant transgenic readout lines.



Global Proteomics and Proteogenomics

Global Proteomics and Proteogenomics Proteogenomics is a new exciting field in biological mass spectrometry that combines proteomics information with sample specific genomic and transcriptomics information. Applications in proteogenomics include discovery […]



Glycoproteomics

Glycoproteomics The Proteomics Core Facility (PCF) at University of Gothenburg will provide the national demand for access to expertise and instrumentation for advanced glycosylation analysis. Glycosylation is among the most […]



Human Antibody Therapeutics

Human Antibody Therapeutics The Human Antibody Therapeutics unit supports the development of therapeutic antibodies. The unit will assist by isolating human antibodies from in-house constructed IP free phage libraries towards […]



In Situ Sequencing

In Situ Sequencing The in situ sequencing (ISS) unit provides spatially resolved gene expression data for panels of genes at subcellular resolution. The technique has been developed in the lab of Mats […]



In Vitro and Systems Pharmacology

This unit aims at a thorough understanding of the in vitro pharmacology of a candidate drug therapy (single drug or a drug mixture) using relevant model systems and systemic molecular and phenotypic profiling techniques in combination with computational systemic/network and synergy analyses.



Integrated Microscopy Technologies

Support advanced light microscopy (ALM), electron microscopy (FIB-SEM) and correlative array tomography (CAT) projects



Medicinal Chemistry – Hit2Lead

The Medicinal Chemistry – Hit2Lead unit identifies promising early small molecule leads for further optimization.



Microbial Single Cell Genomics

Provides streamlined single-cell sorting, lysis, whole-genome amplification and screening of individual microbial cells, as well as whole genome and targeted gene sequencing services.



National Bioinformatics Infrastructure (NBIS)

Provides custom-tailored support with data analysis, computational tools, systems development and training.



National Genomics Infrastructure (NGI)

The National Genomics Infrastructure (NGI) provides services for next generation sequencing and SNP genotyping on all scales using a comprehensive range of modern technology



NGI Stockholm

NGI Stockholm consists of two groups; Genomics Production and Genomics Applications Development, and offers state-of-the-art service in the rapidly developing field of massively parallel DNA sequencing.



NGI Uppsala

National Genomics Infrastructure – Uppsala NGI Uppsala offers next generation sequencing (NGS) and genotyping services of high quality using the latest technologies to academic researchers in Sweden and abroad. NGI […]



Protein Expression and Characterization

The Protein Expression and Characterization unit provides recombinant proteins needed for biochemical screening and therapeutic applications as well as antigens for human antibody production using bacterial and mammalian expression systems.



Spatial Mass Spectrometry

Spatial Mass Spectrometry Spatial mass spectrometry is a label-free method that allows for the visualization and quantitative analysis of the distribution of targeted or untargeted chemical species directly in tissue […]



Spatial omics

Provides services for a variety of tools for spatially resolved molecular profiling in tissue sections for both gene and protein expression.



Spatial Proteomics

Has a unique and near proteome wide collection of polyclonal antibodies. These reagents can be applied in your research project to perform targeted proteomics in cell lines and tissue sections.



Spatial Transcriptomics

Spatial Transcriptomics is a method that allows visualization and quantitative analysis of the transcriptome in individual tissue sections



Structural Proteomics

Structural Proteomics The Structural Proteomics infrastructure unit provides access to cutting-edge equipment and expertise, for analysis of protein interactions and conformational dynamics with mass spectrometry. The unit is part of […]



Swedish Metabolomics Centre (SMC)

Performs targeted and untargeted mass spectrometry based analysis of metabolites and lipids. The focus is tailor-made solutions for researchers.



Swedish NMR Centre

Provide structure determination and dynamic characterization of proteins including their interactions with ligands and other biomolecules.



Target Product Profiling & Drug Safety Assessment

Target Product Profiling & Drug Safety Assessment This unit gives support to principal investigators and innovation agencies in preparing a first target product profile, assists with platform and project coordination, […]



Last updated: 2022-12-21

Content Responsible: Lars Johansson(lars.johansson@scilifelab.se)