• Mapping human tissue architecture using spatial transcriptomics

    Omer Ali Bayraktar, PhDWellcome Sanger Institute, UK Abstract Spatial transcriptomic technologies promise to resolve cellular wiring diagrams of tissues in health and disease, but comprehensive mapping of cell types in situ remains a challenge. First, I will present сell2location, a principled Bayesian model that can resolve fine-grained cell types in spatial transcriptomic data and create […]

    Joakim Lundeberg
    Air&Fire, SciLifeLab Stockholm Tomtebodavägen 23A, Solna, Sweden
  • Spatial analysis of gene expression in tissues

    Single-cell genomics technologies have become widely used to study heterogeneous and dynamic biological systems. In order to meet the growing demand for a deeper understanding of tissue profiling, a number of different spatial transcriptomics approaches have been developed and applied successfully. The goal of this practical course is to provide participants with an overview of […]

    Joakim Lundeberg
    Air&Fire, SciLifeLab Stockholm Tomtebodavägen 23A, Solna, Sweden

    Solid tumours as dynamic cellular ecosystems

    Dr. Alex Swarbrick, Garvan Institute for Medical Research, Australia Location: Air/FireDate: 10.00 24th of May Abstract: A well-established principle in developmental biology is that cellular context governs cell fate, differentiation, proliferation and survival. There is emerging evidence that solid tumours are also complex cellular systems, or ecosystems, in which interactions between neoplastic, stromal and immune […]

    Joakim Lundeberg
    Air&Fire, SciLifeLab Stockholm Tomtebodavägen 23A, Solna, Sweden