Developmental origins of cell heterogeneity in the human lung
HDCA Seminar Series 2022 | Lung Christo Samakovlis and Alexandros Sountoulidis The lung contains numerous specialized cell-types with distinct roles in tissue function and integrity. To clarify the origins and mechanisms generating cell heterogeneity, we created a first comprehensive topographic atlas of early human lung development. We report 83 cell states, several spatially-resolved developmental trajectories and predict cell interactions within defined […]